It is a next generation skin healing therapy which simultaneously results in physical(peeling) and chemical effects through injecting the strong-pressure CO2 gas to instantaneously peel the dermis layer and sequentially injecting the valid drug before the peeled dermis layer closes up. Since Synergy Fill uses the CO2 gas to peel the dermis layer and sequentially injects the drug into the produced air pocket, the drug gets evenly distributed, and, thereby, results in immediate skin improvement effects.